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首页> 外文OA文献 >EXPERIMENTAL EPIDEMIOLOGY OF TUBERCULOSIS : HEREDITARY RESISTANCE TO ATTACK BY TUBERCULOSIS AND TO THE ENSUING DISEASE AND THE EFFECT OF THE CONCENTRATION OF TUBERCLE BACILLI UPON THESE TWO PHASES OF RESISTANCE
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EXPERIMENTAL EPIDEMIOLOGY OF TUBERCULOSIS : HEREDITARY RESISTANCE TO ATTACK BY TUBERCULOSIS AND TO THE ENSUING DISEASE AND THE EFFECT OF THE CONCENTRATION OF TUBERCLE BACILLI UPON THESE TWO PHASES OF RESISTANCE

机译：结核病的实验流行病学：遗传性抵抗结核病的侵袭和随之而来的疾病以及结核杆菌浓度在这两个阶段的影响

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摘要

1. Hereditary resistance to attack by air-borne tubercle bacilli is distinct from the resistance to the ensuing disease. 2. One inbred rabbit family has little resistance to attack: by the microorganism but has considerable resistance against the ensuing disease. 3. Another inbred family has considerable resistance against attack by the tubercle bacillus but has little resistance against the ensuing disease. 4. Increasing concentrations of tubercle bacilli in the environment of the family of high genetic resistance to the disease increase the incidence of infection, accelerate the onset of the disease, and affect its essential character in proportion to the concentration of the microorganism. 5. Up to a certain concentration of tubercle bacilli in the environment of the families of low genetic resistance to the disease, increasing concentrations of the infectious agent also increase the incidence of the disease and accelerate its onset, although its anatomical character is always of a uniform rapidly progressive type. Beyond this concentration further increment of the infectious agent exercises no effect.
机译：1.对空中传播的结核杆菌侵袭的遗传抵抗力与对随之而来的疾病的抵抗力截然不同。 2.一个近交兔家族几乎没有抵抗力：受到微生物的攻击，但对随之而来的疾病具有相当大的抵抗力。 3.另一个近交家庭对结核杆菌的攻击具有相当大的抵抗力，但对随之而来的疾病却几乎没有抵抗力。 4.在对该疾病具有高遗传抗性的家庭的环境中，结核杆菌的浓度增加，增加了感染的发生率，加速了疾病的发作，并与微生物的浓度成比例地影响了其基本特征。 5.在对疾病具有低遗传抗性的家庭的环境中，直至达到一定浓度的结核杆菌，增加感染剂的浓度也会增加疾病的发病率并加速疾病的发作，尽管其解剖学特征始终具有统一快速进步型。超过该浓度，传染原的进一步增加没有作用。

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    Lurie, Max B.;

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  • 年度 1944
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  • 正文语种 {"code":"en","name":"English","id":9}
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